Univ.-Prof. Dr. Verena Dirsch
Verena Dirsch


Resetar, M, Tietcheu Galani, BR, Tsamo, AT, Chen, Y, Schachner, D, Stolzlechner, S, Mawouma Pagna, JI, Beniddir, MA, Kirchmair, J & Dirsch, VM 2023, 'Flindissone, a Limonoid Isolated from Trichilia prieuriana, Is an LXR Agonist', Journal of Natural Products, vol. 86, no. 8, pp. 1901-1909. https://doi.org/10.1021/acs.jnatprod.3c00059



Lapinskaite, R, Atalay, HN, Malatinec, Š, Donmez, S, Cinar, ZO, Schwarz, P, Perhal, AF, Císařová, I, Labanauskas, L, Karpiński, TM, Dirsch, V, Tumer, TB & Rycek, L 2023, 'Synthesis of Selagibenzophenone A and Its Derivatives for Evaluation of Their Antiproliferative, RORγ Inverse Agonistic, and Antimicrobial Effect', Chemistry SELECT, vol. 8, no. 7.




Pferschy-Wenzig, E-M, Ortmann, S, Atanasov, AG, Hellauer, K, Hartler, J, Kunert, O, Gold-Binder, M, Ladurner, A, Heiß, EH, Latkolik, S, Zhao, Y-M, Raab, P, Monschein, M, Trummer, N, Samuel, B, Crockett, S, Miao, J-H, Thallinger, GG, Bochkov, V, Dirsch, VM & Bauer, R 2022, 'Characterization of Constituents with Potential Anti-Inflammatory Activity in Chinese Lonicera Species by UHPLC-HRMS Based Metabolite Profiling', Metabolites, vol. 12, no. 4, 288. https://doi.org/10.3390/metabo12040288

Linder, T, Papaplioura, E, Ogurlu, D, Geyrhofer, S, Hummelbrunner, S, Schachner, D, Atanasov, AG, Mihovilovic, MD, Dirsch, VM & Schnürch, M 2022, 'Investigation of Leoligin Derivatives as NF-κΒ Inhibitory Agents', Biomedicines, vol. 10, no. 1, 62. https://doi.org/10.3390/biomedicines10010062



Atanasov, AG, Zotchev, SB, Dirsch, VM, the International Natural Product Sciences Taskforce & Supuran, CT 2021, 'Natural products in drug discovery: advances and opportunities', Nature Reviews Drug Discovery, vol. 20, pp. 200-216. https://doi.org/10.1038/s41573-020-00114-z


Ladurner, A, Linder, T, Wang, L, Hiebl, V, Schuster, D, Schnürch, M, Mihovilovic, MD, Atanasov, AG & Dirsch, VM 2020, 'Characterization of a structural leoligin analog as farnesoid X receptor agonist and modulator of cholesterol transport', Planta Medica, vol. 86, no. 15, pp. 1097-1107. https://doi.org/10.1055/a-1171-8357

Dao-Huy, T, Latkolik, S, Bräuer, J, Pfeil, A, Stuppner, H, Schnürch, M, Dirsch, VM & Mihovilovic, MD 2020, 'Structural features defining nf-κb inhibition by lignan-inspired benzofurans and benzothiophenes', Biomolecules, vol. 10, no. 8, 1131. https://doi.org/10.3390/biom10081131



Resetar, M, Liu, X, Herdlinger, S, Kunert, O, Pferschy-Wenzig, E-M, Latkolik, S, Steinacher, T, Schuster, D, Bauer, R & Dirsch, VM 2020, 'Polyacetylenes from Oplopanax horridus and Panax ginseng: Relationship between Structure and PPARγ Activation', Journal of Natural Products, vol. 83, no. 4, pp. 918-926. https://doi.org/10.1021/acs.jnatprod.9b00691

RXR and ROR as targets for natural products and structural analogs.

Verena Dirsch (Speaker)

3 Nov 20235 Nov 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


RXR and ROR as targets for natural products and structural analogs.

Verena Dirsch (Speaker)

23 Oct 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


RXR and ROR as targets for natural product (analogs).

Verena Dirsch (Speaker)

4 Sep 20237 Sep 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


RXR and ROR as targets for natural products and structural analogs.

Verena Dirsch (Speaker)

1 Dec 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Impulse lecture: career options in academia.

Verena Dirsch (Speaker) & Judith Maria Rollinger (Speaker)

19 May 202220 May 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Einfluss des Neolignans Honokiol auf die intestinale Barrierefunktion

Anja Baumann (Speaker), Elisabeth Habersatter (Contributor), Daniel Schachner (Contributor), Verena Dirsch (Contributor) & Ina Bergheim (Contributor)

17 Mar 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Neolignan analogs lead to a selective RXR modulator.

Verena Dirsch (Speaker)

24 Sep 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


From man to mice to molecules.

Verena Dirsch (Speaker)

5 Apr 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


Discovery of new GPBAR1 agonists by combined in silico - in vitro screening

Benjamin Kirchweger (Speaker), Jadel Müller Kratz (Contributor), Angela Ladurner (Contributor), Ulrike Grienke (Contributor), Verena Dirsch (Contributor), Thierry Langer (Contributor) & Judith Maria Rollinger (Contributor)

26 Aug 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Neolignan derivatives as RXR selective modulators – A promising approach against metabolic disease?

Verena Dirsch (Speaker)

12 Jun 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Neolignan-derived rexinoids: promising modulators in metabolic disease?

Verena Dirsch (Speaker)

2 May 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Neolignan-derived rexinoids: promising modulators in metabolic disease?

Verena Dirsch (Speaker)

19 Apr 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Das Berufsbild des Hochschullehrers im Wandel, Symposium: Hochschullehrer 2030 – endangered species or global player.

Verena Dirsch (Speaker)

20 Oct 2017

Activity: Talks and presentationsTalk or oral contributionScience to Science


Pharmacognosy and Pharmacology: two sides of one coin?

Verena Dirsch (Speaker)

30 Sep 2016

Activity: Talks and presentationsTalk or oral contributionOther


From man to mice to molecules.

Verena Dirsch (Speaker)

16 May 2016

Activity: Talks and presentationsTalk or oral contributionOther


RXRα and neolignans – a promising approach against metabolic disease?

Verena Dirsch (Speaker)

11 Apr 2016

Activity: Talks and presentationsTalk or oral contributionOther


Bioactives from Natural Sources – a Vienna perspective.

Verena Dirsch (Speaker)

7 Oct 2015

Activity: Talks and presentationsTalk or oral contributionOther


Bioactives from Natural Sources – new opportunities using approaches from molecular biology.

Verena Dirsch (Speaker)

16 Oct 2014

Activity: Talks and presentationsTalk or oral contributionOther


Neolignans: from PPARγ to RXRα

Verena Dirsch (Speaker)

25 Sep 2014

Activity: Talks and presentationsTalk or oral contributionOther


Biosimilars.

Verena Dirsch (Speaker)

24 May 2014

Activity: Talks and presentationsTalk or oral contributionOther


Natural products in vascular biology - molecular mechanisms.

Verena Dirsch (Invited speaker)

22 Nov 2012

Activity: Talks and presentationsTalk or oral contributionOther


Natural products as leads and tools in cardiovascular research.

Verena Dirsch (Invited speaker)

4 Oct 2012

Activity: Talks and presentationsTalk or oral contributionOther


Leads and Lessons from Natural Products.

Verena Dirsch (Invited speaker)

12 Dec 2011

Activity: Talks and presentationsTalk or oral contributionOther


Naturstoffe in der Gefäßbiologie – Molekulare Wirkmechanismen.

Verena Dirsch (Invited speaker)

1 Dec 2011

Activity: Talks and presentationsTalk or oral contributionOther


Bioactive natural products targeting inflammation.

Verena Dirsch (Invited speaker)

23 Sep 2011

Activity: Talks and presentationsTalk or oral contributionOther


Natural products as leads and tools in cardiovascular research.

Verena Dirsch (Invited speaker)

16 Jun 2011

Activity: Talks and presentationsTalk or oral contributionOther


Natural products and redox regulation.

Verena Dirsch (Invited speaker)

15 Jul 2010

Activity: Talks and presentationsTalk or oral contributionOther


Effect of roscovitine and derivatives in PDGF-activated VSMC.

Verena Dirsch (Invited speaker)

14 Jun 2010

Activity: Talks and presentationsTalk or oral contributionOther


Natural products as leads and tools in cardiovascular research

Verena Dirsch (Invited speaker)

20 Nov 2009

Activity: Talks and presentationsTalk or oral contributionOther


Leads and Lessons from Nature

Verena Dirsch (Invited speaker)

17 Oct 2009

Activity: Talks and presentationsTalk or oral contributionOther


Naturstoffe in der Gefäßbiologie – molekulare Wirkmechanismen

Verena Dirsch (Speaker)

21 Jul 2009

Activity: Talks and presentationsTalk or oral contributionOther


Virtual and real screening of natural products to find effective modulators of protein tyrosine phosphatase PTP1B.

Verena Dirsch (Contributor)

18 Apr 2009

Activity: Talks and presentationsTalk or oral contributionOther


Natural products – leads and lessons

Verena Dirsch (Speaker)

3 Mar 2009

Activity: Talks and presentationsTalk or oral contributionOther


Vasoprotection by inhibition of vascular smooth muscle cell growth and migration.

Verena Dirsch (Invited speaker)

18 Jul 2008

Activity: Talks and presentationsTalk or oral contributionOther


Natural product-driven chemical biology: a useful concept for target identification?

Verena Dirsch (Invited speaker)

11 Jul 2008

Activity: Talks and presentationsTalk or oral contributionOther


Leads and lessions from natural products.

Verena Dirsch (Invited speaker)

5 May 2008

Activity: Talks and presentationsTalk or oral contributionOther


Austrian red wines and their effects on endothelial nitric oxide synthase

Verena Dirsch (Contributor)

25 Apr 2008

Activity: Talks and presentationsTalk or oral contributionOther


Antioxidantien, pflanzliche Polyphenole: was können Rotwein und Co?

Verena Dirsch (Invited speaker)

26 Oct 2007

Activity: Talks and presentationsTalk or oral contributionOther


Gefäßschutz durch Zellwachstumshemmung - vom Naturstoff zum Target

Verena Dirsch (Invited speaker)

10 Oct 2007

Activity: Talks and presentationsTalk or oral contributionOther


Natural products and chronic inflamnmatory vascular processes.

Verena Dirsch (Invited speaker)

2 Sep 2007

Activity: Talks and presentationsTalk or oral contributionOther


Selective inhibition of platelet-derived growth factor-induced signalling cascades by indirubin-3'-monoxime

Verena Dirsch (Contributor)

2 Sep 2007

Activity: Talks and presentationsTalk or oral contributionOther


Chronic resveratrol induces a redox- dependent senescent-like growth arrest - role of the S-phase arrest

Verena Dirsch (Contributor)

13 Mar 2007

Activity: Talks and presentationsTalk or oral contributionOther


Effects of indirubin-3`-monoxime on platelet-derived growth factor signaling

Verena Dirsch (Contributor)

6 Sep 2006

Activity: Talks and presentationsTalk or oral contributionOther


Natural products: small molecule tools to probe for pharmacological targets?

Verena Dirsch (Contributor)

18 Nov 2005

Activity: Talks and presentationsTalk or oral contributionOther


Rotwein - die angenehme Art dem Herzinfarkt vorzubeugen ?

Verena Dirsch (Speaker)

18 Oct 2005

Activity: Talks and presentationsTalk or oral contributionOther


Naturstoffe - nicht nur ideal zur Wirkstoff- sondern auch zur Targetsuche?

Verena Dirsch (Contributor)

20 Jun 2005

Activity: Talks and presentationsTalk or oral contributionOther


Mit einem Naturstoff auf Target-Suche: Shp2, ein Hemmer vaskulärer Hypertrophie?

Verena Dirsch (Contributor)

28 Jan 2005

Activity: Talks and presentationsTalk or oral contributionOther


Rotweinpolyphenole - die angenehme Art dem Herzinfarkt vorzubeugen?

Verena Dirsch (Contributor)

26 Oct 2004

Activity: Talks and presentationsTalk or oral contributionOther


Resveratrol hemmt die Angiotensin II-induzierte Hypertrophie in vaskulären glatten Muskelzellen - aber über welches Target?

Verena Dirsch (Contributor)

28 Jun 2004

Activity: Talks and presentationsTalk or oral contributionOther


Polyphenole aus dem Rotwein - eine Erklärung für das "French Paradox"?

Verena Dirsch (Contributor)

25 May 2004

Activity: Talks and presentationsTalk or oral contributionOther


Mittels Resveratrol von der Angiotensin II-induzierten Hypertrophie zur Phosphatase Shp2

Verena Dirsch (Contributor)

24 May 2004

Activity: Talks and presentationsTalk or oral contributionOther


Resveratrol: Einfluss auf Proliferation/Zellzyklus und die Angiotensin II-induzierte Hypertrophy von vaskulären glatten Muskelzellen.

Verena Dirsch (Contributor)

21 Apr 2004

Activity: Talks and presentationsTalk or oral contributionOther


NO French Paradox without red wine polyphenols?

Verena Dirsch (Contributor)

31 Mar 2004

Activity: Talks and presentationsTalk or oral contributionOther


Naturstoffe als Tools?: was uns Resveratrol über das Angiotensin II Signaling in vaskulären glatten Muskelzellen erzählt......

Verena Dirsch (Contributor)

28 Jan 2004

Activity: Talks and presentationsTalk or oral contributionOther


Resveratrol and other cardiovascular active natural products.

Verena Dirsch (Contributor)

19 Jun 2003

Activity: Talks and presentationsTalk or oral contributionOther


Resveratrol: Einfluss auf Proliferation und Zellzyklus von vaskulären glatten Muskelzellen

Verena Dirsch (Contributor)

4 Jun 2003

Activity: Talks and presentationsTalk or oral contributionOther


Resveratrol: Mechanismen der Wachstumshemmung von vaskulären glatten Muskelzellen

Verena Dirsch (Contributor)

28 Apr 2003

Activity: Talks and presentationsTalk or oral contributionOther


Mechanism of vascular smooth muscle cell growth arrest by resveratrol

Verena Dirsch (Contributor)

22 Apr 2003

Activity: Talks and presentationsTalk or oral contributionOther


Einfluss von Resveratrol auf Zellzyklus und Proliferation von vaskulären glatten Muskelzellen

Verena Dirsch (Contributor)

9 Apr 2003

Activity: Talks and presentationsTalk or oral contributionOther


Resveratrol: Mechanismen der Wachstumshemmung von glatten Muskelzellen

Verena Dirsch (Contributor)

16 Dec 2002

Activity: Talks and presentationsTalk or oral contributionOther


Vasoprotective compounds made by nature?

Verena Dirsch (Contributor)

27 Jun 2002

Activity: Talks and presentationsTalk or oral contributionOther



Resveratrol, eine vielversprechende Substanz zur Prävention von Atherosklerose?

Verena Dirsch (Contributor)

10 Dec 2001

Activity: Talks and presentationsTalk or oral contributionOther


Cell-based techniques for the discovery and characterisation of anti-inflammatory natural products

Verena Dirsch (Invited speaker)

8 Oct 2001

Activity: Talks and presentationsTalk or oral contributionOther


Das Triterpen-Chinonmethid Pristimerin hemmt die Induktion der induzierbaren NO-Synthase in LPS-aktivierten RAW 264.7 Makrophagen

Verena Dirsch (Invited speaker)

2 Dec 1998

Activity: Talks and presentationsTalk or oral contributionOther


Der Einfluß von Allicin und Ajoen. zwei Verbindungen aus dem Knoblauch, auf die induzierbare NO-Synthase

Verena Dirsch (Speaker)

8 May 1998

Activity: Talks and presentationsTalk or oral contributionOther


Department of Pharmaceutical Sciences

Deputy Head

Josef-Holaubek-Platz 2 (UZA II)
1090 Wien
Room: 2G452

T: +43-1-4277-55270

verena.dirsch@univie.ac.at