Univ.-Prof. Mag. Dr. Thierry Langer
Thierry Langer





Bampali, K, Koniuszewski, F, Vogel, FD, Fabjan, J, Andronis, C, Lekka, E, Virvillis, V, Seidel, T, Delaunois, A, Royer, L, Rolf, MG, Giuliano, C, Traebert, M, Roussignol, G, Fric-Bordat, M, Mazelin-Winum, L, Bryant, SD, Langer, T & Ernst, M 2023, 'GABAA receptor-mediated seizure liabilities: a mixed-methods screening approach', Cell Biology and Toxicology, vol. 39, no. 6, pp. 2793-2819. https://doi.org/10.1007/s10565-023-09803-y



Gehringer, M, Pape, F, Méndez, M, Barbie, P, Unzue Lopez, A, Lefranc, J, Klingler, FM, Hessler, G, Langer, T, Diamanti, E & Schiedel, M 2023, 'Back in Person: Frontiers in Medicinal Chemistry 2023', ChemMedChem, vol. 18, no. 19, e202300344. https://doi.org/10.1002/cmdc.202300344



Kalaba, P, Pacher, K, Neill, PJ, Dragacevic, V, Zehl, M, Wackerlig, J, Kirchhofer, M, Sartori, SB, Gstach, H, Kouhnavardi, S, Fabisikova, A, Pillwein, M, Monje-Quiroga, F, Ebner, K, Prado-Roller, A, Singewald, N, Urban, E, Langer, T, Pifl, C, Lubec, J, Leban, JJ & Lubec, G 2023, 'Chirality Matters: Fine-Tuning of Novel Monoamine Reuptake Inhibitors Selectivity through Manipulation of Stereochemistry', Biomolecules, vol. 13, no. 9, 1415. https://doi.org/10.3390/biom13091415


Pojtanadithee, P, Hengphasatporn, K, Suroengrit, A, Boonyasuppayakorn, S, Wilasluck, P, Deetanya, P, Wangkanont, K, Sukanadi, IP, Chavasiri, W, Wolschann, P, Langer, T, Shigeta, Y, Maitarad, P, Sanachai, K & Rungrotmongkol, T 2023, 'Identification of Promising Sulfonamide Chalcones as Inhibitors of SARS-CoV-2 3CLpro through Structure-Based Virtual Screening and Experimental Approaches', Journal of Chemical Information and Modeling, vol. 63, pp. 5244-5258. https://doi.org/10.1021/acs.jcim.3c00663





Lubec, J, Hussein, AM, Kalaba, P, Feyissa, DD, Arias-Sandoval, E, Cybulska-Klosowicz, A, Bezu, M, Stojanovic, T, Korz, V, Malikovic, J, Aher, NY, Zehl, M, Dragacevic, V, Leban, JJ, Sagheddu, C, Wackerlig, J, Pistis, M, Correa, M, Langer, T, Urban, E, Höger, H & Lubec, G 2023, 'Low-Affinity/High-Selectivity Dopamine Transport Inhibition Sufficient to Rescue Cognitive Functions in the Aging Rat', Biomolecules, vol. 13, no. 3, 467. https://doi.org/10.3390/biom13030467


Towards Next Generation Pharmacophore Modeling: Concepts and Applications

Thierry Langer (Speaker)

21 Dec 2022

Activity: Talks and presentationsTalk or oral contributionScience to Public


Pharmacophore Models: Useful Tools for Bio-Active Compound Identification, Optimization, and Profiling

Thierry Langer (Speaker)

15 Dec 2022

Activity: Talks and presentationsTalk or oral contributionScience to Public


Pharmacophores: Versatile Tools for Computer-Assisted Molecular Design

Thierry Langer (Speaker)

18 Jul 2022

Activity: Talks and presentationsTalk or oral contributionScience to Public


Approaches to Next Generations Pharmacophore Modeling

Thierry Langer (Speaker)

29 Jun 2022

Activity: Talks and presentationsTalk or oral contributionScience to Public


Pharmacophores: Versatile Tools for Computer-Assisted Molecular Design

Thierry Langer (Speaker)

25 May 2022

Activity: Talks and presentationsTalk or oral contributionScience to Public


In silico and in vitro Approach to Assess Direct Allosteric AMPK Activators from Nature

Benjamin Kirchweger (Speaker), Andreas Wasilewicz (Contributor), Katrin Fischhuber (Contributor), Ammar Tahir (Contributor), Ya Chen (Contributor), Elke Heiß (Contributor), Thierry Langer (Contributor), Johannes Kirchmair (Contributor) & Judith Maria Rollinger (Contributor)

20 May 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Academic Drug Discovery: Pittfalls and Bottlenecks

Thierry Langer (Speaker)

11 May 2022

Activity: Talks and presentationsTalk or oral contributionScience to Public


A Computational Approach to Identify Potential Novel Inhibitors Against The Coronavirus SARS-CoV-2

Ernst Urban (Speaker), Thierry Langer (Speaker), Thomas Seidel (Speaker), Oliver Wieder (Speaker) & Arthur Garon (Speaker)

28 Jul 2020

Activity: Talks and presentationsTalk or oral contributionScience to Science


New Approaches to Analyze Big Data: The Molecular Dynamics Trajectory Case

Thierry Langer (Speaker)

28 Nov 2019

Activity: Talks and presentationsTalk or oral contributionOther


Towards Next Generation Pharmacophores: Concepts and Applications

Thierry Langer (Speaker)

24 Nov 2019

Activity: Talks and presentationsTalk or oral contributionOther


Adventures in Computer-Assisted Molecular Design

Thierry Langer (Speaker)

16 Sep 2019

Activity: Talks and presentationsTalk or oral contributionOther


Towards Next Generation Pharmacophores: Concepts and Applications

Thierry Langer (Speaker)

21 May 2019

Activity: Talks and presentationsTalk or oral contributionOther


Towards next Generation Pharmacophores: Concepts and Application

Thierry Langer (Speaker)

20 Mar 2019

Activity: Talks and presentationsTalk or oral contributionScience to Public


Towards Next Generation Pharmacophores: Concepts and Applications

Thierry Langer (Speaker)

20 Mar 2019

Activity: Talks and presentationsTalk or oral contributionOther


Pharmacophore Modelling: How to Enhance Virtual Screening Efficacy in Early Drug Discovery

Thierry Langer (Speaker)

23 Jan 2019

Activity: Talks and presentationsTalk or oral contributionOther


Discovery of new GPBAR1 agonists by combined in silico - in vitro screening

Benjamin Kirchweger (Speaker), Jadel Müller Kratz (Contributor), Angela Ladurner (Contributor), Ulrike Grienke (Contributor), Verena Dirsch (Contributor), Thierry Langer (Contributor) & Judith Maria Rollinger (Contributor)

26 Aug 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Pharmacophore-based Analysis of MD Trajectories: Towards Understanding KD of Protein Ligands

Thierry Langer (Speaker)

5 Jul 2018

Activity: Talks and presentationsTalk or oral contributionOther


Pharmacophore-based Analysis of MD Trajectories: Towards Understanding KD of Protein Ligands

Thierry Langer (Speaker)

2 Jul 2018

Activity: Talks and presentationsTalk or oral contributionOther


Adventures in Computer-Assisted Molecular Design

Thierry Langer (Speaker)

29 Jun 2018

Activity: Talks and presentationsTalk or oral contributionOther


Generation of Structure-based Pharmacophore Models in Protein Binding Sites Obtained from Molecular Dynamics Simulations

Thierry Langer (Speaker)

29 May 2018

Activity: Talks and presentationsTalk or oral contributionOther


Pharmacophore-based Analysis of MD Trajectories: Towards Understanding KD of Protein Ligands

Thierry Langer (Speaker)

22 May 2018

Activity: Talks and presentationsTalk or oral contributionOther


In silico tools for early phase side effect profiling and off target prediction of potential drug candidates

Thierry Langer (Speaker)

5 Apr 2018

Activity: Talks and presentationsTalk or oral contributionOther


MD Derived Feature-based Pharmacophores: A New Way to Enhance Virtual Screening Efficacy in Multitarget Drug Discovery

Thierry Langer (Speaker)

16 Mar 2018

Activity: Talks and presentationsTalk or oral contributionOther


Dynamic Pharmacophores: A New Way to Enhance Virtual Screening Efficacy in Early Drug Discovery

Thierry Langer (Speaker)

28 Jan 2018

Activity: Talks and presentationsTalk or oral contributionOther


Dynamic Pharmacophores: A New Way to Enhance Virtual Screening Efficacy in Early Drug Discovery

Thierry Langer (Speaker)

16 Nov 2017

Activity: Talks and presentationsTalk or oral contributionOther


In Silico Tools for Early Drug Discovery

Thierry Langer (Speaker)

14 Nov 2017

Activity: Talks and presentationsTalk or oral contributionOther


Metabolism & Bioisosteres in Medicinal Chemistry

Thierry Langer (Speaker)

19 Oct 2017

Activity: Talks and presentationsTalk or oral contributionOther


Activity Profiling & Toxicity Prediction Using Inte:Ligand's LigandScout KNIME Extensions

Thierry Langer (Speaker)

9 Oct 2017

Activity: Talks and presentationsTalk or oral contributionOther


Adventures in Computer-Aided Molecular Design

Thierry Langer (Speaker)

12 Sep 2017

Activity: Talks and presentationsTalk or oral contributionOther


Towards next Generation Pharmacophore Models: Concepts and Applications

Thierry Langer (Speaker)

25 Aug 2017

Activity: Talks and presentationsTalk or oral contributionOther


3D Pharmacophores for Hit and Lead Identification: Current and Future Aspects

Thierry Langer (Speaker)

26 May 2017

Activity: Talks and presentationsTalk or oral contributionOther


Dynamic Pharmacophore and the Common Hits Approach: A Novel Method for Enhancing Virtual Screening Efficiency

Thierry Langer (Speaker)

23 May 2017

Activity: Talks and presentationsTalk or oral contributionOther


Dynamic pharmacophores and the common hits approach: a novel method for enhancing virtual screening efficiency

Thierry Langer (Speaker)

23 May 2017

Activity: Talks and presentationsTalk or oral contributionOther


3D Pharmacophores for Hit and Lead Identification: Current and Future Aspects

Thierry Langer (Speaker)

26 Apr 2017

Activity: Talks and presentationsTalk or oral contributionOther


Pharmacophore Approaches for Polypharmacoliogical Profiling of Compound Libaries

Thierry Langer (Speaker)

8 Feb 2017

Activity: Talks and presentationsTalk or oral contributionOther


Introduction to Ligand-Based Drug Design: Pharmacophore Methods

Thierry Langer (Speaker)

18 Jan 2017

Activity: Talks and presentationsTalk or oral contributionOther


Seminarvortrag

Thierry Langer (Speaker)

12 Dec 2016

Activity: Talks and presentationsTalk or oral contributionOther


Department of Pharmaceutical Sciences

Head

Josef-Holaubek-Platz 2 (UZA II)
1090 Wien
Room: 2D306

T: +43-1-4277-55103

thierry.langer@univie.ac.at