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Sharon Bryant, MBA MSc
Bampali, K, Koniuszewski, F, Vogel, FD, Fabjan, J, Andronis, C, Lekka, E, Virvillis, V, Seidel, T, Delaunois, A, Royer, L, Rolf, MG, Giuliano, C, Traebert, M, Roussignol, G, Fric-Bordat, M, Mazelin-Winum, L, Bryant, SD, Langer, T & Ernst, M 2023, 'GABAA receptor-mediated seizure liabilities: a mixed-methods screening approach', Cell Biology and Toxicology, vol. 39, no. 6, pp. 2793-2819. https://doi.org/10.1007/s10565-023-09803-y
Kohlbacher, SM, Ibis, G, Permann, C, Bryant, S, Langer, T & Seidel, T 2023, 'A new set of KNIME nodes implementing the QPhAR algorithm', Molecular Informatics, vol. 42, no. 5, 2200245. https://doi.org/10.1002/minf.202200245
Bryant, SD, Seidel, T, Heider, J, Langer, T, Ernst, M, Kohlbacher, SM, Bampali, K, Koniuszewski, F, Virvilis, V, Lekka, E, Persidis, A, Mayache, M-A & Weissmann, D 2022, 'The NeuroDeRisk toolbox: DeRisking chemical structures for neurotoxic adverse outcomes', Toxicology Letters, vol. 368, no. Suppl.1, pp. S82-S82. https://doi.org/10.1016/j.toxlet.2022.07.239, https://doi.org/10.1016/j.toxlet.2022.07.239
Bryant, S & Langer, T 2021, 'Successful Drug Discovery, Volume 5. Edited by János Fischer, Christian Klein, and Wayne E. Childers', ChemMedChem, vol. 17, no. 9. https://doi.org/10.1002/cmdc.202100705
Wieder, O, Kuenemann, M, Wieder, M, Seidel, T, Meyer, C, Bryant, SD & Langer, T 2021, 'Improved lipophilicity and aqueous solubility prediction with composite graph neural networks', Molecules, vol. 26, no. 20, 6185. https://doi.org/10.3390/molecules26206185
Tomašič, T, Zubrienė, A, Skok, Ž, Martini, R, Pajk, S, Sosič, I, Ilaš, J, Matulis, D & Bryant, SD 2021, 'Selective DNA gyrase inhibitors: Multi-target in silico profiling with 3D-pharmacophores', Pharmaceuticals, vol. 14, no. 8, 789. https://doi.org/10.3390/ph14080789
Garon, A, Wieder, O, Bareis, K, Seidel, T, Ibis, G, Bryant, S, Theret, I, Ducrot, P & Langer, T 2020, 'Hierarchical Graph Representation of Pharmacophore Models', Frontiers in Molecular Biosciences, vol. 7, 599059. https://doi.org/10.3389/fmolb.2020.599059, https://doi.org/10.3389/fmolb.2020.599059
Ramsay, RR, Basile, L, Maniquet, A, Hagenow, S, Pappalardo, M, Saija, MC, Bryant, SD, Albreht, A & Guccione, S 2020, 'Parameters for Irreversible Inactivation of Monoamine Oxidase', Molecules (Basel, Switzerland), vol. 25, no. 24, 5908. https://doi.org/10.3390/molecules25245908
Tomašič, T, Durcik, M, Keegan, BM, Skledar, DG, Zajec, Ž, Blagg, BSJ & Bryant, SD 2020, 'Discovery of novel HSP90 C-Terminal inhibitors using 3D-pharmacophores derived from molecular dynamics simulations', International Journal of Molecular Sciences, vol. 21, no. 18, 6898, pp. 1-22. https://doi.org/10.3390/ijms21186898
Langer, T & Bryant, SD 2020, 'Successful Drug Discovery, Volume 4: Edited by János Fischer, Christian Klein, and Wayne E. Childers' ChemMedChem, vol. 15, no. 1, pp. 173-173. https://doi.org/10.1002/cmdc.201900599
Bryant, SD, Langer, T, Martini, R, Ramilo-Gomes, F, Guedes, RC & Marques, MM 2019, 'Structure and ligand-based design of promising small molecule EZH2 inhibitors', American Chemical Society. Abstracts of Papers (at the National Meeting), vol. 258. <https://www.acsmedchem.org/data/258th-National-ACS-Meeting-mediabstractf2019.pdf>
Muchtaridi, M, Yusuf, M, Syahidah, HN, Subarnas, A, Zamri, A, Bryant, S & Langer, T 2019, 'Cytotoxicity Of Chalcone Of Eugenia aquea Burm F. Leaves Against T47D Breast Cancer Cell Lines And Its Prediction As An Estrogen Receptor Antagonist Based On Pharmacophore-Molecular Dynamics Simulation', Advances and Applications in Bioinformatics and Chemistry, vol. 12, pp. 33-43. https://doi.org/10.2147/AABC.S217205
Ortuso, F, Bagetta, D, Maruca, A, Talarico, C, Bolognesi, ML, Haider, N, Borges, F, Bryant, S, Langer, T, Senderowitz, H & Alcaro, S 2018, 'The Mu.Ta.Lig. Chemotheca: A Community-Populated Molecular Database for Multi-Target Ligands Identification and Compound-Repurposing', Frontiers in Chemistry, vol. 6, 130. https://doi.org/10.3389/fchem.2018.00130
Muchtaridi, M, Syahidah, HN, Subarnas, A, Yusuf, M, Bryant, SD & Langer, T 2017, 'Molecular Docking and 3D-Pharmacophore Modeling to Study the Interactions of Chalcone Derivatives with Estrogen Receptor Alpha', Pharmaceuticals, vol. 10, no. 4, 81. https://doi.org/10.3390/ph10040081
Bryant, S, Langer, T, Seidel, T, Ibis, G & Poli, G 2017, 3D Pharmacophore Modeling Techniques in Computer‐Aided Molecular Design Using LigandScout. in A Varnek (ed.), Tutorials in Chemoinformatics. Wiley VCH. https://doi.org/10.1002/9781119161110
Kellici, T, Ntountaniotis, D, Vrontaki, E, Liapakis, G, Moutevelis-Minakakis, P, Kokotos, G, Hadjikakou, S, Tzakos, AG, Afantitis, A, Melagraki, G, Bryant, S, Langer, T, Di Marzo, V & Mavromoustakos, T 2015, 'Rational Drug Design Paradigms: The Odyssey for Designing Better Drugs', Combinatorial Chemistry & High Throughput Screening, vol. 18, no. 3, pp. 238-256. https://doi.org/10.2174/1386207318666150305125638
Hardy, B, Affentranger, R, Contini, A, Gutierrez de Teran, H, Spitzner, J, Papoian, R, Seibel, WI, Nelson, S, Wiseman, J, Bryant, S, Lucet, I & Doerig, C 2013, Collaborative Drug Design of Plasmodium Kinase Inhibitors. in C Doerig, G Spaeth & M Wiese (eds), Protein phosphorylation in parasites: novel targets for antiparasitic intervention. Wiley VCH, Weinheim, Drug discovery in infectious diseases, vol. 5, pp. 375-416. https://doi.org/10.1002/9783527675401.ch18, https://doi.org/10.1002/9783527675401.ch18
Bryant, S & Langer, T 2013, Data Mining Using Ligand Profiling and Target Fishing. in R Hoffman, A Gohier & P Pospisil (eds), Data Mining in Drug Discovery. Wiley VCH, Methods and Principles in Medicinal Chemistry. https://doi.org/10.1002/9783527655984
Langer, T & Bryant, SD 2013, Computational methods for drug target profiling and polypharmacology. in In Silico Drug Discovery and Design. Future Science. https://doi.org/10.4155/EBO.13.417
Koulouridi, E, Langer, T, Bryant, SD & Mavromoustakos, T 2013, 'Rational approach for the discovery of lead-compounds using pharmacophore models. The use of Drug Databank zinc in virtual screening', Pharmakeutikē.

Department of Pharmaceutical Sciences

Josef-Holaubek-Platz 2 (UZA II)
1090 Wien

sharon.bryant@univie.ac.at