Details

[Back]

Assoz. Prof. Dipl.-Biochem. Dr. Elke Heiß, Privatdoz.

T: +43-1-4277-55993

elke.heiss@univie.ac.at

Summer term 2026

321031 PR Biochemische und vertiefende pharmazeutisch-chemische Arbeitstechniken - B17 - (7 Kurse)

322028 VU Ausgewählte Kapitel aus der pharmakognostischen Forschung - M13

580003 SE Academic Journey Club

580004 SE Chemical Genetics - practice and methods

Winter term 2025

321017 VO Biochemie und Immunologie - B10

321031 PR Biochemische und vertiefende pharmazeutisch-chemische Arbeitstechniken - B17 - (5 Kurse)

322028 VU Ausgewählte Kapitel aus der pharmakognostischen Forschung - M13

323004 VO Drug Discovery - MPS3

580005 SE SE Chemical Genetics - practice and methods

580006 SE Academic Journey Club

Summer term 2025

321031 PR Biochemische und vertiefende pharmazeutisch-chemische Arbeitstechniken - B17 - (6 Kurse)

321037 VU Pharmazeutische Wissenschaften - B20

321131 PR Biochemische und vertiefende pharmazeutisch-chemische Arbeitstechniken - B17 - Zusatzkurse - (4 Kurse)

322028 VU Ausgewählte Kapitel aus der pharmakognostischen Forschung - M13

580003 SE Professional Journey Club

580004 SE Chemical Genetics - practice and methods

Braunböck-Müller, B & Heiß, E 2025, 'Impact of cell culture conditions on NRF2 (nuclear factor E2 p45-related factor 2)-driven reporter gene expression', Advances in Redox Research, vol. 16, 100136. https://doi.org/10.1016/j.arres.2025.100136

Petsouki, E, Gerakopoulos, V, Gianniou, DD, Heiß, E & Trougakos, IP 2025, 'Involvement of NRF2 and AMPK signaling in aging and progeria: a digest', Redox biology, vol. 85, 103782. https://doi.org/10.1016/j.redox.2025.103782

Korczak, M, Redl, M, Roszkowski, P, Granica, S, Rollinger, JM , Heiss, E & Piwowarski, JP 2025, 'Synthesis, characterization, and anti-inflammatory potential of serotonin- and dopamine-conjugates of urolithin A', Biomedicine & Pharmacotherapy, vol. 189, 118282. https://doi.org/10.1016/j.biopha.2025.118282

Pfleger, T , Ortmayr, K , Steiner, K, Zaher, R, Seiser, S, Elbe-Bürger, A, Heiß, E & Klang, V 2025, 'Radical scavenging effect of skin delivery systems using Korean red ginseng extract and assessment of their biocompatibility with human primary dermal fibroblasts and HaCaT keratinocytes', International Journal of Pharmaceutics, vol. 674, 125477. https://doi.org/10.1016/j.ijpharm.2025.125477

Cannavacciuolo, C, Napolitano, A, Dirsch, VM , Heiss, EH, Masullo, M & Piacente, S 2025, 'Oleraceins from Portulaca oleracea leaves: Quali-quantitative determination and antioxidant potential', Current Research in Food Science, vol. 10, 100992. https://doi.org/10.1016/j.crfs.2025.100992

Li, W, Cai, Z, Schindler, F, Afjehi-Sadat, L, Montsch, B, Heffeter, P, Heiss, EH & Weckwerth, W 2024, 'Elevated PINK1/Parkin-Dependent Mitophagy and Boosted Mitochondrial Function Mediate Protection of HepG2 Cells from Excess Palmitic Acid by Hesperetin', Journal of Agricultural and Food Chemistry, vol. 72, no. 23, pp. 13039-13053. https://doi.org/10.1021/acs.jafc.3c09132

Bahiraii, S, Braunböck-Müller, B & Heiss, EH 2024, 'Increased Glycolytic Activity Is Part of Impeded M1(LPS) Macrophage Polarization in the Presence of Urolithin A ^#', Planta Medica, vol. 90, no. 7-8, pp. 546-553. https://doi.org/10.1055/a-2240-7462

Heiß, E & Rollinger, JM (eds) 2024, 'Special Issue Celebrating the Austrian Pharmacognosy', Planta Medica: natural products and medicinal plant research, vol. 90, no. 7-8, pp. 496-497. https://doi.org/10.1055/a-2285-6455

Cai, Z, Li, W , Hager, S, Wilson, JL, Afjehi-Sadat, L , Heiss, EH, Weichhart, T, Heffeter, P & Weckwerth, W 2024, 'Targeting PHGDH reverses the immunosuppressive phenotype of tumor-associated macrophages through α-ketoglutarate and mTORC1 signaling', Cellular and Molecular Immunology, vol. 21, no. 5, pp. 448-465. https://doi.org/10.1038/s41423-024-01134-0

Bahiraii, S, Brenner, M, Yan, F, Weckwerth, W & Heiss, EH 2024, 'Corrigendum: Sulforaphane diminishes moonlighting of pyruvate kinase M2 and interleukin 1β expression in M1 (LPS) macrophages(Front. Immunol., (2022), 13, (935692), 10.3389/fimmu.2022.935692)', Frontiers in Immunology, vol. 15, 1395642. https://doi.org/10.3389/fimmu.2024.1395642

Bahiraii, S, Brenner, M, Weckwerth, W & Heiss, EH 2024, 'Sulforaphane impedes mitochondrial reprogramming and histone acetylation in polarizing M1 (LPS) macrophages', Free Radical Biology and Medicine, vol. 213, pp. 443-456. https://doi.org/10.1016/j.freeradbiomed.2024.01.029

Rollinger, JM & Heiß, E 2024, 'Special Issue Celebrating the Austrian Pharmacognosy', Planta Medica: natural products and medicinal plant research, vol. 90, no. 07/08, pp. 496-497. https://doi.org/10.1055/a-2285-6455

Petsouki, E, Ender, S, Sosa Cabrera, SN & Heiss, EH 2023, 'AMPK-Mediated Phosphorylation of Nrf2 at S374/S408/S433 Favors Its βTrCP2-Mediated Degradation in KEAP1-Deficient Cells', Antioxidants, vol. 12, no. 8, 1586. https://doi.org/10.3390/antiox12081586

Cannavacciuolo, C, Cerulli, A, Dirsch, VM , Heiss, EH, Masullo, M & Piacente, S 2023, 'LC-MS- and ¹H NMR-Based Metabolomics to Highlight the Impact of Extraction Solvents on Chemical Profile and Antioxidant Activity of Daikon Sprouts (Raphanus sativus L.)', Antioxidants, vol. 12, no. 8, 1542. https://doi.org/10.3390/antiox12081542

Blažević, T, Ciotu, CI, Gold-Binder, M, Heiss, EH, Fischer, MJM & Dirsch, VM 2023, 'Cultured rat aortic vascular smooth muscle cells do not express a functional TRPV1', PLoS ONE, vol. 18, no. 2, e0281191. https://doi.org/10.1371/journal.pone.0281191

Li, W, Cai, Z, Schindler, F, Bahiraii, S, Brenner, M , Heiss, EH & Weckwerth, W 2023, 'Norbergenin prevents LPS-induced inflammatory responses in macrophages through inhibiting NFκB, MAPK and STAT3 activation and blocking metabolic reprogramming', Frontiers in Immunology, vol. 14, 1117638, pp. 1-20. https://doi.org/10.3389/fimmu.2023.1117638

Cai, Z, Li, W , Brenner, M, Bahiraii, S, Heiss, EH & Weckwerth, W 2022, 'Branched-chain ketoacids derived from cancer cells modulate macrophage polarization and metabolic reprogramming', Frontiers in Immunology, vol. 13, 966158. https://doi.org/10.3389/fimmu.2022.966158

Boakye, YD, Osafo, N, Oppong-Kyekyeku, J, Abotsi, WKM, Boakye-Gyasi, E, Heiss, E & Agyare, C 2022, 'Regulation of Nrf2 and NF-κB activities may contribute to the anti-inflammatory mechanism of xylopic acid', Inflammopharmacology : experimental and therapeutic studies, vol. 30, no. 5, pp. 1835-1841. https://doi.org/10.1007/s10787-022-00950-y

Cannavacciuolo, C, Napolitano, A, Heiss, EH , Dirsch, VM & Piacente, S 2022, 'Portulaca oleracea, a rich source of polar lipids: Chemical profile by LC-ESI/LTQOrbitrap/MS/MSn and in vitro preliminary anti-inflammatory activity', Food Chemistry, vol. 388, 132968. https://doi.org/10.1016/j.foodchem.2022.132968

Petsouki, E, Cabrera, SNS & Heiss, EH 2022, 'AMPK and NRF2: Interactive players in the same team for cellular homeostasis?', Free Radical Biology & Medicine, vol. 190, pp. 75-93. https://doi.org/10.1016/j.freeradbiomed.2022.07.014

NRF2 in diologue with AMP-activated kinase and cellular energy metabolism

Heiß, E. (Speaker)

6 Jun 2025

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Immunometabolic responses of macrophages to Nrf2 activation

Heiß, E. (Speaker)

5 Mar 2025

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Nrf2 at the crossroad of cellular energy metabolism and stress response

Heiß, E. (Speaker)

20 Feb 2025

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Natural products at the interface between cellular energy metabolism and stress response

Heiß, E. (Speaker)

31 Oct 2024

Activity: Talks and presentations › Talk or oral contribution › Science to Science

NRF2, natural products and type 2 diabetes- a clar cut picture?

Heiß, E. (Speaker)

27 Jun 2024

Activity: Talks and presentations › Talk or oral contribution › Science to Science

NRF2- Driver and Passenger of Cellular Metabolism

Heiß, E. (Speaker)

26 Jun 2024

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Immunometabolic Responses Elicited by Sulforaphane in murine M1 (LPS) polarizing macrophages

Heiß, E. (Speaker)

19 Apr 2024

Activity: Talks and presentations › Talk or oral contribution › Science to Science

In silico and in vitro Approach to Assess Direct Allosteric AMPK Activators from Nature

Kirchweger, B. (Speaker), Wasilewicz, A. (Contributor), Fischhuber, K. (Contributor), Tahir, A. (Contributor), Chen, Y. (Contributor), Heiß, E. (Contributor), Langer, T. (Contributor), Kirchmair, J. (Contributor) & Rollinger, J. M. (Contributor)

20 May 2022

Activity: Talks and presentations › Talk or oral contribution › Science to Science

AMP(K)lifying the Nrf2 dependent stress response

Heiß, E. (Speaker)

10 Jan 2022

Activity: Talks and presentations › Talk or oral contribution › Science to Science

AMP(K)lifying Nrf2: : The crosstalk between Nrf2 and the metabolic regulator AMPK

Heiß, E. (Speaker)

2022

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Natural products at the interface of cellular metabolism and stress response

Heiß, E. (Speaker)

7 Sept 2021

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Identification of AMPK-dependent phosphorylation sites in the transcription factor Nrf2 and their functional relevance in cells

Matzinger, M. (Speaker), Fischhuber, K. (Contributor), Mechtler, K. (Contributor) & Heiß, E. (Contributor)

30 Sept 2018 → 4 Oct 2018

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Combinatory effects of glutathione-modulation on the toxicity of deoxynivalenol (DON) and NX-3 and its co-regulated metabolite butenolide (BUT)

Wölflingseder, L. (Keynote speaker), Del Favero, G. (Contributor), Heiß, E. (Contributor), Adam, G. (Contributor) & Marko, D. (Contributor)

11 Jun 2018

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Natural products at the interface of cellular metabolism and phenotypic response

Heiß, E. (Speaker)

2018

Activity: Talks and presentations › Talk or oral contribution › Science to Science

: Bioactivity screening for xylopic acid as well as geraniin and its gut metabolites in cell-based assays

Heiß, E. (Speaker)

2017

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Molekulare Mechanismen von Naturprodukten- Forschungsspielerei oder Praxisrelevanz?

Heiß, E. (Speaker)

26 Oct 2016

Activity: Talks and presentations › Talk or oral contribution › Science to Public