Assoz. Prof. Mag. Dr. Anna Weinzinger, Privatdoz.
T: +43-1-4277-55311
Shalomov, B, Friesacher, T, Yakubovic, D, Carlo Combista, J, Reddy, HP, Dabbah, S, Bernsteiner, H, Zangerl-Plessl, EM, Weinzinger, A & Dascal, N 2025, 'Ethosuximide: Subunit- and Gβγ-dependent blocker and reporter of allosteric changes in GIRK channels', British Journal of Pharmacology, vol. 182, no. 8, pp. 1704-1718. https://doi.org/10.1111/bph.17446

Li, E, Boujeddaine, N, Houtman, MJC, Maas, RGC, Sluijter, JPG, Ecker, GF, Stary-Weinzinger, A, van Ham, WB & van der Heyden, MAG 2024, 'Development of new Kir2.1 channel openers from propafenone analogues', British Journal of Pharmacology, vol. 182, no. 3, pp. 633-650. https://doi.org/10.1111/bph.17377






Hackl, B, Lukacs, P, Ebner, J, Pesti, K, Haechl, N, Földi, MC, Lilliu, E, Schicker, K, Kubista, H, Stary-Weinzinger, A, Hilber, K, Mike, A, Todt, H & Koenig, X 2022, 'The Bradycardic Agent Ivabradine Acts as an Atypical Inhibitor of Voltage-Gated Sodium Channels', Frontiers in Pharmacology, vol. 13, 809802. https://doi.org/10.3389/fphar.2022.809802

Friesacher, T, Reddy, HP, Bernsteiner, H, Carlo Combista, J, Shalomov, B, Bera, AK, Zangerl-Plessl, EM, Dascal, N & Stary-Weinzinger, A 2022, 'A selectivity filter mutation provides insights into gating regulation of a K+ channel', Communications Biology, vol. 5, no. 1, 345. https://doi.org/10.1038/s42003-022-03303-1



Qile, M, Golden, TD, Houtman, MJC, Weinzinger, A, van der Heyden, MAG, van Ham, W, Romunde, FL, Fransen, D, IJzerman, AP, January, CT, Heitman, LH & Delisle, BP 2020, 'LUF7244 plus dofetilide rescues aberrant Kv11.1 trafficking and produces functional IKv11.1', Molecular Pharmacology, vol. 97, no. 6, pp. 355-364. https://doi.org/10.1124/mol.119.118190





Qile, M, Beekman, HDM, Sprenkeler, DJ, Houtman, MJC, van Ham, W, Weinzinger, A, Beyl, S, Hering, S, van den Berg, D-J, de Lange, ECM, Heitman, LH, IJzerman, AP, Vos, MA & van der Heyden, M 2019, 'LUF7244, an allosteric modulator/activator of K(v)11.1 channels, counteracts dofetilide-induced torsades de pointes arrhythmia in the chronic atrioventricular block dog model', British Journal of Pharmacology, vol. 176, no. 19, pp. 3871-3885. https://doi.org/10.1111/bph.14798




GNB1: Mutations, Protein Interactions, and Drug Repurposing

Anna Weinzinger (Speaker)

24 Jun 2025

Activity: Talks and presentationsTalk or oral contributionScience to Public


GIRK2 DRUG REPURPOSING SCREEN IDENTIFIES TREATMENT OPTIONS FOR PATIENTS SUFFERING FROM EXTREMELY RARE DISEASES

Michael Netzer (Speaker), Steffen Hering (Contributor), Nathan Dascal (Contributor) & Anna Weinzinger (Contributor)

16 Feb 2025

Activity: Talks and presentationsTalk or oral contributionScience to Science


Allosteric mechanisms of inward rectifier K+ channel gating probed by disease mutants and ethosuximide

Anna Weinzinger (Speaker)

12 Sept 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


Allosteric regulation of GIRK K+ channels

Anna Weinzinger (Speaker)

9 Jul 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


Allosteric mechanisms of inward rectifier K+ channel gating

Anna Weinzinger (Speaker)

23 Jun 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


Challenges in drug repurposing for rare diseases – the GNB1/KCNJ6 example

Anna Weinzinger (Speaker)

12 Sept 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Probing Inward Rectifier K+ Channel Gating and Conductance Guided by Disease Mutations

Anna Weinzinger (Speaker)

21 Jun 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


Computational investigation of a rare disease

Theres Friesacher (Speaker) & Anna Weinzinger (Contributor)

Sept 2022 → …

Activity: Talks and presentationsTalk or oral contributionScience to Science


Visualizing individual protonation events in Kir2 channels

Michael Jirout (Speaker), Eva Maria Zangerl-Plessl (Contributor) & Anna Weinzinger (Contributor)

Sept 2022 → …

Activity: Talks and presentationsTalk or oral contributionScience to Science


Computational investigations of ion channels

Anna Weinzinger (Speaker)

15 Sept 201920 Sept 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


FASEB: The Ion Channel Regulation Conference: Molecules to Disease

Anna Weinzinger (Speaker)

7 Jul 201912 Jul 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


Structure-dynamics-function relationships of inward rectifier K+ channels probed by in silico methods

Anna Weinzinger (Speaker)

27 Mar 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Computational investigations of cation channels

Anna Weinzinger (Speaker)

19 May 2017

Activity: Talks and presentationsTalk or oral contributionScience to Science


In silico modelling and drug interactions in Kir6.1

Anna Weinzinger (Speaker)

4 Oct 2016

Activity: Talks and presentationsTalk or oral contributionOther


Molecular modeling of Cantu Syndrome Channels

Anna Weinzinger (Speaker)

10 Sept 2015

Activity: Talks and presentationsTalk or oral contributionOther


Computational investigations of hERG K+ channels

Anna Weinzinger (Speaker)

10 Aug 2015

Activity: Talks and presentationsTalk or oral contributionOther


MD SIMULATIONS OF KIRBAC1.1 MUTANTS REVEAL GATING CHANGES AT THE BUNDLE CROSSING REGION

Anna Weinzinger (Speaker)

4 Feb 2013

Activity: Talks and presentationsTalk or oral contributionOther


Investigating the structural basis of hERG channel block guided by molecular dynamics simulations

Anna Weinzinger (Speaker)

25 Sept 2012

Activity: Talks and presentationsTalk or oral contributionOther


In silico modelling of Kir2.x channels

Anna Weinzinger (Speaker)

2011 → …

Activity: Talks and presentationsTalk or oral contributionScience to Science


IK1 block by small molecules

Anna Weinzinger (Speaker)

2010 → …

Activity: Talks and presentationsTalk or oral contributionOther


In silico prediction of the cardiotoxicity of drug candidates

Anna Weinzinger (Speaker)

2008 → …

Activity: Talks and presentationsTalk or oral contributionScience to Science


Modelling the hERG K+ channel

Anna Weinzinger (Speaker)

2008 → …

Activity: Talks and presentationsTalk or oral contributionScience to Science


Towards a consensus model of the hERG K+ channel

Anna Weinzinger (Speaker)

2008 → …

Activity: Talks and presentationsTalk or oral contributionOther


Computer modeling strategies to investigate the molecular basis of odor discrimination

Anna Weinzinger (Speaker)

2006 → …

Activity: Talks and presentationsTalk or oral contributionScience to Science


Department of Pharmaceutical Sciences

Josef-Holaubek-Platz 2 (UZA II)
1090 Wien
Room: 2D178

T: +43-1-4277-55311

anna.stary@univie.ac.at